发明名称 |
Formulations for delivery of osteogenic proteins |
摘要 |
A composition is disclosed comprising a pharmaceutically acceptable admixture of an osteogenic protein; a porous particulate polymer matrix; an osteogenic protein-sequestering amount of blood clot; and a calcium sulfate hemihydrate-containing substance. Also disclosed are formulations of bone morphogenetic proteins with improved solubility and/or stability characteristics. |
申请公布号 |
AU7953794(A) |
申请公布日期 |
1995.03.27 |
申请号 |
AU19940079537 |
申请日期 |
1994.09.02 |
申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
KALVIN W. K YIM;MICHAEL C HUBERTY;RICHARD P. NORTHEY JR.;RICHARD A KENLEY;JAY A. SCHRIER;JENNIFER L SMITH;JOHN J STECKERT;C. MICHAEL PHILBROOK;PATRICK JOSEPH DESOUZA |
分类号 |
A61L27/00;A61K38/00;A61K38/18;A61L27/22;A61L27/26;A61P19/00 |
主分类号 |
A61L27/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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