摘要 |
<p>Compounds of formula (I) and pharmaceutically acceptable salts thereof in which R1 represents a C1-6 alkyl group optionally substituted by one or more hydroxy groups; R2 represents a C2-6 alkoxycarbonyl group; and R3, R4 and R5 independently represent hydrogen, halo, a halogenated C1-6 alkyl group in which at least one halogen atom is attached to the carbon atom which is attached to the naphthyridine ring, or a halogenated C1-6 alkoxy group in which at least one halogen atom is attached to the carbon atom which is attached to the oxygen atom of the alkoxy group; provided that at least one of R3, R4 and R5 represents a group other than hydrogen; are disclosed, which are antirheumatic agents. Compositions containing these compounds and processes to make them are also disclosed.</p> |