摘要 |
<p>A method of retarding vascular leakage caused by tissue injury comprises administering a neurotensin-related compound at a dosage sufficient to prevent or retard injury induced vascular leakage following injury or before deliberate injury. Neurotensin-related compounds of this invention have a peptide domain with sequences Pro-Trp-Ile-Leu (SEQ ID NO:1), Pro-Tyr-Ile-Leu (SEQ ID NO:2), Pro-Trp-Leu-Xaa (SEQ ID NO:3), or Pro-Tyr-Leu-Xaa (SEQ ID NO:4) where Xaa is N-methyl-leucine.</p> |