Gene coding for a protein regulating aureobasidin sensitivity.

摘要

An isolated gene coding for a protein regulating aureobasidin sensitivity. A process for cloning the gene with the use of the gene or a part of the same as a probe. A nucleic acid probe being hybridizable with the gene. An antisense DNA or RNA of the gene. A recombinant or transformant having the gene contained therein. An isolated protein regulating aureobasidin sensitivity and a process for producing the same by using the transformant. An antibody for the protein. A process for detecting the protein or the gene. A process for screening an antimycotic by using the protein or the transformant. This invention is useful in the diagnosis and treatment of diseases including mycoses.