发明名称 Use of local anesthetics for the manufacture of a medicament for the protection of plasma cell membranes.
摘要 <p>A number of new therapeutic uses have been found for compounds such as known local anesthetics which are quite different from the present therapeutic uses of these drugs. The uses include, for example; modulating lymphocytes, macrophages and other immune cell functions, or PMN functions; inhibiting the cytotoxic effect of polymorphonuclear neutrophils leucocytes; providing a protective effect on plasma cell membranes; and providing an antidote against intoxication by intoxicants. A further new use has been found for treating subject suffering from neoplastic diseases of diverse cell or tissue origin by the administration of an effective amount of lidocaine or a related substance. It has been found that this new use provides a reduction and/or inhibition of tumor growth.</p>
申请公布号 EP0643964(A2) 申请公布日期 1995.03.22
申请号 EP19940112854 申请日期 1994.08.17
申请人 MEDIPHARMA S.A. 发明人 MAHIQUES, JUAN CARLOS;ELICABE, RICARDO LUIS;KOLER, RAUL ISIDORO;LAGUENS, RUBEN MARTIN;PORTIANSKY, ENRIQUE LEO
分类号 A61K31/165;A61K31/245;A61K31/47;A61K31/445;(IPC1-7):A61K31/16 主分类号 A61K31/165
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