| 摘要 |
<p>PCT No. PCT/FR92/00034 Sec. 371 Date Oct. 19, 1993 Sec. 102(e) Date Oct. 19, 1993 PCT Filed Jan. 16, 1992 PCT Pub. No. WO92/13098 PCT Pub. Date Aug. 6, 1992.Method for diagnosing a cellular aging or inflammation condition of keratinocytes of the skin or a pilous follicle in a person, or for diagnosing the efficiency of a treatment intended to combat said condition. To this effect, the concentration or activity of certain markers (catalase, glutathion or glutathion peroxydase) is compared in the keratinocytes suspected of being pathological and the keratinocytes of a reference non pathological area. The pathological condition intensifies the activity of the catalase, or reduces the activity of other markers. Application particularly to the diagnosis of alopecia, and to the estimation of the efficiency of a treatment of baldness with minoxidil in a given individual.</p> |
