| 摘要 |
PCT No. PCT/FR91/00536 Sec. 371 Date Jan. 21, 1993 Sec. 102(e) Date Jan. 21, 1993 PCT Filed Jul. 3, 1991 PCT Pub. No. WO92/00982 PCT Pub. Date Jan. 23, 1992.Process for the preparation of nitride complexes of transition metals for use as radiopharmaceutical products or for the synthesis of novel pharmaceutical products. The process consists in reacting an oxygenic transition metal compound such as 99mTc, 186Re or 188Re, with a first nitrogenous ligand such as sodium nitride or a nitrogenous compound such as S-methyl, N-methyl dithiocarbazate, and a reducing agent consisting of either tin (II) or a dithionite. The product so obtained can be used for the preparation of radiopharmaceutical products by a reaction with a second ligand such as sodium dithiocarbamate.
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