发明名称 DNA gyrase inhibitors, process for their manufacture and pharmaceutical preparations containing same
摘要 Compounds of the formula <IMAGE> II in which P is hydroxy and T is the group -X2-CR7aR7b-CHR8-OH or T is hydrogen and P is the group O-CHR8-CR7aR7b-X2-OH and, wherein X1, X2, R1, R2, R3, R4, R5, R6, R7a, R7b, and R8 are as defined in the specification, or a reactive derivative thereof. These compounds are useful in the preparation of DNA gyrase inhibitors.
申请公布号 US5399741(A) 申请公布日期 1995.03.21
申请号 US19940177483 申请日期 1994.01.06
申请人 HOFFMANN-LA ROCHE INC. 发明人 ARISAWA, MIKIO;GOETSCHI, ERWIN;HEBEISEN, PAULFAELLO;KAMIYAMA, TSUTOMU;LINK, HELMUT;MASCIADRI, RAFFAELLO;SHIMADA, HISAO;WATANABE, JUNKO
分类号 A61K31/395;A61K31/42;A61K31/425;A61K38/00;A61P31/04;C07C317/24;C07C317/28;C07C317/46;C07C317/48;C07C323/56;C07C323/58;C07C323/64;C07D291/08;C07D413/04;C07D413/14;C07D417/04;C07D417/14;C07D419/04;C07D419/12;C07K5/02;C07K5/078;C07K5/097;C07K5/103;C07K7/06;(IPC1-7):C07F7/04 主分类号 A61K31/395
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