发明名称 |
Cyclic antimicrobial peptides and preparation thereof. |
摘要 |
<p>A polypeptide compound of the following general formula : <CHEM> wherein R<1> is hydrogen, R<2> is acyl group, R<3> is hydroxy or acyloxy, R<4> is hydroxy or hydroxysulfonyloxy, R<5> is hydrogen or lower alkyl which may have one or more suitable substituent (s), and R<6> is hydrogen, hydroxy or acyl (lower) alkylthio and a pharmaceutically acceptable salt thereof, processes for their preparation and pharmaceutical compositions comprising them as an active ingredient.</p> |
申请公布号 |
EP0644199(A1) |
申请公布日期 |
1995.03.22 |
申请号 |
EP19940107406 |
申请日期 |
1994.05.12 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
OHKI, HIDENORI;TOMISHIMA, MASAKI;YAMADA, AKIRA;TAKASUGI, HISASHI |
分类号 |
A61K31/40;A61K38/00;A61K38/12;A61P31/04;A61P31/10;C07D487/14;C07K1/113;C07K7/06;C07K7/56;C07K7/64;(IPC1-7):C07K7/56;C07K1/00 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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