摘要 |
A tris(substituted phenyl)bismuth derivative of the general formula (I) or, if any, a pharmaceutically acceptable salt thereof: <CHEM> äwherein X<1> is Y<1>-NR<1>R<2>Äwherein Y<1> is -SO2- or <CHEM> and each of R<1> and R<2> is, independently of each other, a hydrogen atom, a C1-4 alkyl group or A-Z (wherein A is an alkylene chain which has 2-6 carbon atoms in total and may have a branch having at least two carbon atoms, and Z is OR<3> (wherein R<3> is SiR<4>R<5>R<6> (wherein each of R<4>, R<5> and R<6> is, independently of one another, a C1-4 alkyl group or a phenyl group), a hydrogen atom or a C1-4 alkyl group) or NR<7>R<8> (wherein each of R<7> and R<8> is, independently of each other, a hydrogen atom or a C1-4 alkyl group)) provided that the case where R<1> and R<2> are both hydrogen atoms is exceptedÜ, <CHEM> (wherein R<9> is a C1-4 alkyl group, and R<7> is the same as defined above) or Y<2>-A-Z Äwherein Y<2> is an oxygen atom, - S(O)n- (wherein n is an integer of 0 or 2) or <CHEM> (wherein R<1> is the same as defined above), and A and Z are the same as defined aboveÜ, and each of X<2> and X<3> is, independently of each other, a hydrogen atom or any substituent defined above with respect to X<1>ü. |