摘要 |
PURPOSE:To provide a cell culture tank which prevents the cells from being broken by a strong stress, can culture the cells growing in a fibrous form without pellet formation or lumping, and can prevent the cells immobilized to the support from being peeled off. CONSTITUTION:In a culture tank for mammalian or plant cells and/or cells of microorganisms, the culture tank is provided with a stirring mechanism which can arbitrarily vary the liquid flow rate and turn the flow direction. The mechanism is a cage type of rotor 2 in which the screw blades 10 fitted to the rotation shaft 3 for the rotor and the peripheral blades 9 have the structures to cause the flows reverse to each other. It is preferred that the cell culture installation is provided with a means for observation of the cell conditions and a system for controlling the flow rate and/or the flow direction of the stirring mechanism on the basis of the observation.
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