发明名称 |
T cell receptor variable transcripts as disease related markers |
摘要 |
<p>Methods are provided for determining relations between autoimmune degenerative diseases and specific variable regions of T-cell receptors as associated with the host HLA or T-cells associated with combatting neoproliferative diseases. By identifying the particular T-cell receptors which cause or are the disease in mammals, various prophylactic and therapeutic techniques may be employed for inhibiting the attack of the T-cell receptors on the native protein or tissue enhancing the defense. In addition, individuals may be diagnosed as to their propensity for a particular autoimmune disease or the occurrence of such a disease.</p> |
申请公布号 |
AU1004695(A) |
申请公布日期 |
1995.03.16 |
申请号 |
AU19950010046 |
申请日期 |
1995.01.06 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
LAWRENCE STEINMAN;JORGE OKSENBERG;CLAUDE BERNARD |
分类号 |
A61K35/12;A61K35/14;C12N5/08;C12Q1/68;G01N33/53;G01N33/564;G01N33/569;G01N33/574;(IPC1-7):A61K35/26 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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