DERMATOLOGIC PREPARATION AND NOVEL BENZOIC ACID DERIVATIVE.

摘要

A dermatologic preparation containing at least one of the benzoic acid derivatives represented by general formula (I) and pharmacologically acceptable salts thereof, having a sufficient effect of inhibiting sebum secretion and being free from side effects, thus being safe for the human body, wherein R<1> represents -OH, -OR<3> or -NHR<3>; R<2> represents hydrogen, lower alkyl or lower alkoxy; R represents -OR<4> or (II); R<3> represents alkyl, alkenyl or hydroxyalkyl; R<4> represents C4-C10 linear or branched, saturated or monounsaturated alkyl or cycloalkylalkyl; X represents -O- or -NH-; and n represents 1 or 2. <CHEM>