发明名称 |
MODIFIED PROTEIN AND ITS PRODUCTION |
摘要 |
The present invention is directed to modified proteins and methods of their production. The modified proteins comprise a controllable intervening protein sequence (CIVPS) inserted into a target protein, the CIVPS being capable of excision from the modified protein under predetermined conditions, i.e., increase in temperature, exposure to light, unblocking of amino acid residues by dephosphorylation or deglycosylation. If desired, the modified protein can be subjected to these conditions. The CIVPS may also be inserted into a region that substantially inactivates target protein activity. |
申请公布号 |
JPH0770200(A) |
申请公布日期 |
1995.03.14 |
申请号 |
JP19930340885 |
申请日期 |
1993.12.09 |
申请人 |
NEW INGURANDO BAIOREIBUSU INC |
发明人 |
DONARUDO JII KOOMU;FURANSHIN BII PAARAA;UIRIAMU II JIYATSUKU;MINNKUN KUSUYUU;ROBAATO EI HOTSUJIIZU;KURISUTOFUAA JIEI NOORAN |
分类号 |
C07K1/22;C07K14/195;C07K14/41;C07K14/42;C07K14/47;C07K14/48;C07K14/485;C07K14/52;C07K16/00;C07K19/00;C12N9/12;C12N9/22;C12N9/24;C12N9/38;C12N15/09;C12N15/62;C12N15/66;C12P21/02 |
主分类号 |
C07K1/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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