ARAB PROMOTOR AND PROCESS FOR PRODUCTION OF POLYPEPTIDES CONTAINING CECROPINS BY MICROBIOLOGICAL METHOD

摘要

A polynucleotide molecule expressible in a given host comprising the sequence of the araB promoter operably linked to a gene which is heterologous to said host. The heterologous gene codes for a peptide that is biologically active. The invention also relates to a genetic construct which comprises a first genetic sequence coding for cecropin operably linked to a second genetic sequence coding for a polypeptide which is capable of suppressing the bactericidal effect of the resulting fusion protein towards an otherwise cecropin sensitive bacterium.