PHARMACEUTICAL COMPOSITIONS CONTAINING ANIONIC SURFACTANTS

摘要

Pharmaceutical compositions comprise an enzymatically labile pharmaceutically active agent or a prodrug which is permeable through the intestinal wall, and at least one anionic surfactant which is capable of protecting said active agent or prodrug against deactivation by enzymes. A method for the inhibition of the degradation of an enzymatically labile pharmaceutically active agent or prodrug by gastrointestinal enzymes comprises combining said agent or prodrug with an anionic surfactant.