发明名称 |
Zusammensetzung, Vorrichtung und Verfahren zur Untersuchung einer peroxidativ aktiven Substanz. |
摘要 |
A new and improved test device and method of determining the presence or concentration of a peroxidatively active substance, such as hemoglobin, in a test sample are disclosed. The test device includes a test pad comprising a suitable carrier matrix incorporating an indicator reagent composition capable of interacting with a peroxidatively active substance to produce a detectable or measurable response. In addition, a new and improved indicator reagent composition, comprising an indicator dye, such as a redox indicator, like a benzidine indicator; a hydroperoxide; an amine borate compound having the general structural formula: <CHEM> wherein R1, R2, and R3 are, independently, methyl groups or ethyl groups, and m, n and p are numerals ranging from one to about three; and a buffer, is incorporated into a suitable carrier matrix to provide a more accurate and trustworthy assay of a test sample for a peroxidatively active substance. The improved method and composition are especially useful in the assay of urine for occult blood. |
申请公布号 |
DE69013882(T2) |
申请公布日期 |
1995.03.09 |
申请号 |
DE1990613882T |
申请日期 |
1990.12.14 |
申请人 |
MILES, INC., ELKHART, IND., US |
发明人 |
ALBARELLA, JAMES P., GRANGER, IN 46530, US;PUGIA, MICHAEL J., GRANGER, IN 46530, US |
分类号 |
G01N31/00;C12Q1/28;G01N31/22;G01N33/50;G01N33/52;G01N33/72;(IPC1-7):C12Q1/28 |
主分类号 |
G01N31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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