发明名称 PROCEDE DE PREPARATION DE L'ACIDE D,1-BETABENZOYLAMINO-ISO-BUTYRIQUE
摘要 A two-step process for manufacturing d,l- beta -benzoylamino-isobutyric acid is disclosed, wherein in the first step benzamide is reacted with methacrylonitrile in the presence of an alkaline catalyst in an anhydrous solvent medium at atmospheric pressure, thus obtaining d,l- beta -benzoylamino-isobutyronitrile, which, in the second process step, without necessarily being previously crystallized is directly hydrolyzed to d,l- beta -benzoylamino-isobutyric acid.
申请公布号 BE872139(A1) 申请公布日期 1979.03.16
申请号 BE19780191829 申请日期 1978.11.20
申请人 SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. 发明人
分类号 C07B61/00;B01J23/00;B01J23/04;B01J31/00;B01J31/02;C07C;C07C67/00;C07C231/00;C07C231/06;C07C231/12;C07C233/12;C07C233/82;C07C233/83;C07C255/29;C07J71/00 主分类号 C07B61/00
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