摘要 |
Compounds of formula (I): <CHEM> wherein R<1> is hydrogen or methyl, R<2> is hydrogen or E 2-methyl 2-butenoyloxy, and R<3> is hydrogen or hydroxy, with the proviso that when R<3> is hydrogen, R<1> and R<2> are both hydrogen, and when R<2> is E 2-methyl 2-butenoyloxy, R<1> is methyl; the compound of formula (II): <CHEM> and the compound of formula (III): <CHEM> are obtainable by the fermentation of Streptomyces E225 NC1B 12310 or Streptomyces E225B NC1B 12509. The compounds have anthelmintic utility. |
申请人 |
BEECHAM GROUP P.L.C., BRENTFORD, GB |
发明人 |
BANKS, RHONA MARY, TADWORTH SURREY KT20 7NT, GB;POULTON, MARK EDWARD, TADWORTH SURREY KT20 7NT, GB;BAKER, GEOFFREY HAROLD, EPSOM SURREY KT18 5XQ, GB;DORGAN, RODERICK JOHN, EPSOM SURREY KT185XQ, GB |