DERIVATIVES OF MONIC ACIDS A AND C HAVING ANTIBACTERIAL, ANTIMYCOPLASMATICAL, ANTIFUNGAL AND HERBICIDAL ACTIVITY

摘要

Derivatives of monic acids A and C of formula (I) in which: A is an epoxy moiety or an E-double bond moiety: (i) or (ii); B is selected from (a), (b), (c) (which corresponds to C(OH)=CHCO-B3), (d) in which Q denotes the residue of an optionally substituted aryl or heteroaryl ring; D is a group of atoms for linking B with -CONR1; or B-D represents (E)-C(CH¿3?)=CH; and R?1 and R2¿, which may be the same or different, is each selected from hydrogen or (C¿1-6?)alkyl, (C3-7)cycloalkyl, (C2-6)alkenyl, aryl, aryl(C1-4)alkyl, heterocyclyl, (C1-6)alkylcarbonyl, (C3-7)cycloalkylcarbonyl, (C2-6)alkenylcarbonyl, arylcarbonyl, aryl(C1-4)alkylcarbonyl or heterocyclylcarbonyl, each of which may be optionally substituted, have useful antibacterial, antimycoplasmal, antifungal and herbicidal activity.