发明名称 Pyrimidine and pyridine derivatives, their production and use
摘要 The present invention relates to a compound represented by the general formula (I): <CHEM> [wherein R<1> is a lower alkyl group, a lower cycloalkyl group, a lower alkoxy group, an aliphatic cyclic amino group which may be substituted by one or more lower alkyl groups, or a phenyl group which may be substituted by one or more halogen atoms, R<2> is a hydrogen atom or a lower alkyl group, R<3> and R<4>, which may be the same or different, are hydrogen atoms, halogen atoms, lower alkyl groups, lower haloalkyl groups, lower alkoxy groups or lower alkylthio groups, R<5>, R<6> and R<7>, which may be the same or different, are hydrogen atoms, halogen atoms, lower alkyl groups, lower haloalkyl groups, lower alkoxy groups, lower alkylthio groups or lower dialkylamino groups, and X is =N- or =CH-] or a pharmacologically acceptable salt thereof, which has inhibitory effect on acyl-CoA:cholesterol O-acyltransferase (ACAT), a process for producing said compound, and uses of said compound.
申请公布号 AU6881794(A) 申请公布日期 1995.02.23
申请号 AU19940068817 申请日期 1994.07.29
申请人 NIHON NOHYAKU CO., LTD. 发明人 MASASHI NAGAMINE;KENJI YAMAMOTO;KENJI HORIUCHI;YOSHIMITSU MATSUI;MASANORI YOSHIDA
分类号 C07D213/75;C07D239/42 主分类号 C07D213/75
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