发明名称 |
Kit and method for targeting |
摘要 |
The invention describes a novel kit or method for the delivery of pharmaceutical or diagnostic compounds to target cells in the body. This kit comprises a monospecific antibody with multiple binding sites, which antibody recognizes a target associated antigen, and a ligand-effector moiety, of which the ligand has been derived from the target associated antigen or analogue thereof. Specifically the invention relates to targeting cytotoxic drugs or radioisotopes to tumor cells. The preferred antibody is a human IgM and the ligand is preferably the epitope cognate to said antibody. |
申请公布号 |
ZA9404893(B) |
申请公布日期 |
1995.02.20 |
申请号 |
ZA19940004893 |
申请日期 |
1994.07.06 |
申请人 |
AKZO NOBEL N.V. |
发明人 |
EBO SYBREN BOS;RICHARD P MCCABE |
分类号 |
G01N33/53;A61K;A61K39/395;A61K47/42;A61K47/48;A61K49/00;A61K51/00;B65D;C07K;C07K7/06;C07K16/00;C07K16/18;C07K19/00;C12P21/08;G01N;G01N33/577;G01N33/60 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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