| 发明名称 |
MODIFIED MAXADILAN PROTEIN, ITS PREPARATION AND USE, AND DNA ENCODING THE PROTEIN |
| 摘要 |
A modified maxadilan protein exhibits higher biological activity than native maxadilan from the sand fly Lutzomyia longipalpis. A modified maxadilan fusion protein contains a thrombin cleavage site. This enables the production of the modified maxadilan as a fusion protein and recovery of the modified maxadilan after digestion with thrombin. The modified maxadilan is a potent vasodilator.
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| 申请公布号 |
CA2167489(A1) |
申请公布日期 |
1995.02.16 |
| 申请号 |
CA19942167489 |
申请日期 |
1994.08.05 |
| 申请人 |
SHISEIDO CO., LTD.;GENERAL HOSPITAL CORPORATION (THE) |
发明人 |
TAJIMA, MASAHIRO;OHNUMA, MANAMI;LERNER, ETHAN L. |
| 分类号 |
C12N15/09;A61K38/00;A61P9/08;C07H21/04;C07K14/435;C12N1/21;C12N15/12;C12P21/02;C12R1/19;(IPC1-7):C12N15/62;C07K19/00;A61K38/17 |
主分类号 |
C12N15/09 |
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