发明名称 |
HUMAN GLUCAGON-LIKE 1 PEPTIDE RECEPTOR |
摘要 |
The human GLP-1 receptor is cloned and used in an in vitro assay to screen for compounds that specifically bind to the human GLP-1 receptor, including compounds effective to reduce symptoms of diabetes. The invention includes the assay, the cloned human receptor used in the assay, an isolated human GLP-1 receptor free of other human proteins, and compounds identified through the use of this novel, cloned receptor, which selectively bind the human GLP-1 receptor.
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申请公布号 |
CA2168448(A1) |
申请公布日期 |
1995.02.16 |
申请号 |
CA19942168448 |
申请日期 |
1994.08.03 |
申请人 |
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发明人 |
GRAZIANO, MICHAEL P.;BORKOWSKI, DOREEN A.;CHICCHI, GARY G.;HEY, PATRICIA J.;STRADER, CATHERINE D. |
分类号 |
C12N15/09;A61K38/26;A61P3/08;A61P3/10;C07H21/04;C07K14/605;C07K14/72;C12N5/10;C12N15/12;C12P21/02;C12Q1/02;C12R1/91;(IPC1-7):C12N15/16;G01N33/567 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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