发明名称 Novel macrolides and the use thereof
摘要 Compounds of the formula <IMAGE> in which R1 is hydroxyl, 2-hydroxyethoxy, C1-C4-alkoxy, C1-C4-alkanoyloxy, halogen, amine, azide, a keto, p-nitrobenzenesulphonyl or a pyranyloxy group of the formula <IMAGE> in which X is a group of the formula <IMAGE> or <IMAGE> in which R3 is hydroxyl, C1-C4-alkanoyloxy or organic sulphonyloxy, and R4 is hydroxyl or carbamoyloxy, R2 is hydrogen, hydroperoxy, hydroxyl or methoxy, Y is a group of formula <IMAGE> or <IMAGE> in which R5 is hydroxyl or C1-C4-alkanoyloxy, and R6 and R7 are independently of one another, hydrogen or methyl, are suitable for the production of a drug for the prophylaxis and treatment of diseases which respond to inhibition of the osteoclast proton pump.
申请公布号 ZA9406125(B) 申请公布日期 1995.02.16
申请号 ZA19940006125 申请日期 1994.08.15
申请人 CIBA-GEIGY A. G. 发明人 AXEL ZEECK;KAI UWE BINDSEIL;CLAUDIA BODDIEN
分类号 A61K31/70;A61K31/7042;A61K31/7048;A61P3/00;A61P19/10;A61P43/00;C07D407/06;C07D407/14;C07H17/04;C07H17/08;C12P17/08;C12P19/58 主分类号 A61K31/70
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