Coating prosthetic surfaces with mammalian cells

摘要

A method of coating a prosthetic surface with mammalian cells is disclosed involving placing against the prosthetic surface a composition comprising a substance causing directed growth of endothelial cells and contacting the prosthetic surface, having the composition placed against it, with tissue or a physiological fluid, the tissue or physiological fluid containing mammalian cells, under conditions suitable for the mammalian cells to coat the prosthetic surface. The invention also includes a prosthesis with a surface coated as above with mammalian cells, as well as a method of treating mammals by implanting the above-described prosthesis.