| 摘要 |
2,3-Dihalo-6-nitro substd. oxybenzene cpd. of formula (I) to be useful as an intermediate for preparation of quinoline based antibiotics, is prepd. by: reacting the cpd. of formula (II) with propagyl alcohol in the presence of the basic cpd. in an organic solvent to prepare the cpd. of formula (III) as the intermediate; and then preparing the oxybenzene deriv. (I). In the process, the org. solvent is one or more mixt. of benzene, toluene, halomethane or tetrahydrofuran; the basic cpd. is alkali metal fluoride, alkali (earth) metal hydride, alkali metal carbonate or basic org. solvent cpd.. In the formulas, X1,X2,X3 are halogen.
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