发明名称 |
CRYSTALLINE MODIFICATION OF 2,4-DIOXO-6-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE, METHOD OF OBTAINING THE SAME AND A PHARMACEUTICAL PREPARATION BASED ON IT. |
摘要 |
<p>A new crystalline modification of 2,4-dioxo-6-methyl-1,2,3,4-tetrahydropyrimidine is disclosed, characterized by the interplanar distances (d) and relative reflex intensity (I). The process for obtaining the said substance involves using a cooling agent to cool a solution of 2,4-dioxo-6-methyl-1,2,3,4-tetrahydropyrimidine in water, an organic solvent or a mixture of both, at a rate of at least 6 DEG C per minute until the solution has completely crystallized. The crystals obtained are then removed and dried. The substance claimed has anti-inflammatory properties and promotes the healing of wounds and is the active substance in a preparation used in treating burns and wounds of various types.</p> |
申请公布号 |
EP0638558(A1) |
申请公布日期 |
1995.02.15 |
申请号 |
EP19930905681 |
申请日期 |
1993.01.20 |
申请人 |
LEONIDOV, NIKOLAI BORISOVICH |
发明人 |
LEONIDOV, NIKOLAI BORISOVICH;SELEZENEV, NIKOLAI GEORGIEVICH |
分类号 |
A61K31/505;C07D239/54;(IPC1-7):C07D239/54;A61K47/00 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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