| 发明名称 |
1,4-DIDEOXY-1,4-IMINO-D-MANNITOL-DERIVATE. |
| 摘要 |
<p>Novel derivatives of 1,4-dideoxy-1,4-imino-D-mannitol and method for their synthesis from 4,5-anhydro-1-azido-1-deoxy-2,3-O-isopropylidene-D-talitol or its triflate derivative are disclosed. The novel derivatives, 6-fluoro-1,3-imino-1,4,6-trideoxy-D-mannitol and the N-butyl and N-benzyl derivatives of 1,4-dideoxy-1,4-imino-D-mannitol, have useful mannosidase inhibitory activity.</p> |
| 申请公布号 |
AT117992(T) |
申请公布日期 |
1995.02.15 |
| 申请号 |
AT19900870187T |
申请日期 |
1990.10.15 |
| 申请人 |
MONSANTO COMPANY |
发明人 |
FLEET, GEORGE WILLIAM JOHN;UNIVERSITY OF OXFORD;CARPENTER, NEIL MICHAEL, ICI CHEMICAL;P.O. BOX 90, WILTON CENTRE;WINCHESTER, BRYAN GORDON;UNIVERSITY OF LONDON |
| 分类号 |
A61K31/00;A61K31/40;A61P31/00;A61P31/12;A61P43/00;C07D207/12;C07D317/28;C07D407/04;C07D491/056;C07D493/04;(IPC1-7):C07D207/12 |
主分类号 |
A61K31/00 |
| 代理机构 |
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