发明名称 3-cycloalkyl-prop-2-enamides
摘要 A compound selected from the group consisting of a compound of the formula <IMAGE> I wherein R1 is hydrogen or alkyl of 1 to 3 carbon atoms, W is selected from the group consisting of -O-, -S-, -SO- and -SO2-, Z and Y are -CH- or one is -CH- and the other is -N-, R2, R3, R4, R5 and R6 are individually selected from the group consisting of hydrogen, halogen, methoxy, methylthio, alkyl of 1 to 4 carbon atoms, -WCF3, -CF3, -NO2, -CN-, -W-(CH2)n-CF3, -W-(CF2)n-CF3, -(CF2)n-CF3 and -(CH2)n-CX3, n is an integer from 1 to 3, X is a halogen or R3 and R4 together are -O-(CH2)-O- and R2, R5 and R6 are as defined above, R7 and R8 are individually hydrogen or alkyl of 1 to 6 carbon atoms, R9 is cycloalkyl of 3 to 6 carbon atoms and their non-toxic, pharmaceutically acceptable salts with bases.
申请公布号 US5389652(A) 申请公布日期 1995.02.14
申请号 US19940184566 申请日期 1994.01.21
申请人 ROUSSEL-UCLAF 发明人 KUO, ELIZABETH A.
分类号 A61K31/275;A61K31/277;A61P29/00;A61P37/00;C07C255/23;C07C255/31;C07C317/32;C07C317/40;C07C323/41;C07D213/75;C07D317/40;C07D317/58;C07D317/64;(IPC1-7):A01N43/10 主分类号 A61K31/275
代理机构 代理人
主权项
地址