| 摘要 |
<p>The breakpoints of the pericentric inversion of chromosome 16 have been cloned. Two genes, one at each breakpoint, have also been identified, as well as several forms of the inversion 16 fusion gene. Diagnostic applications for chromosome 16 abnormalities and, particularly acute myeloid leukemia, are also within the scope of the present invention. The figure is a diagrammatic representation of the locations of the human genomic chromosome 16p content of hybrid cells and recombinant clones.</p> |
