发明名称 |
PROSAPOSIN AND CYTOKINE-DERIVED PEPTIDES AS THERAPEUTIC AGENTS |
摘要 |
Prosaposin and peptide derivatives derived therefrom will promote neurite outgrowth in vitro. A peptide consensus sequence was determined by comparing the active neurite outgrowth-inducing saposin C peptide sequence with that of various hematopoietic and neuropoietic cytokines. These cytokine-derived peptides will promote the same processes as their corresponding cytokines. In addition, prosaposin and saposin C promote increased nerve cell myelination ex vivo.
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申请公布号 |
WO9503821(A1) |
申请公布日期 |
1995.02.09 |
申请号 |
WO1994US08453 |
申请日期 |
1994.07.28 |
申请人 |
O'BRIEN, JOHN, S. |
发明人 |
O'BRIEN, JOHN, S.;KISHIMOTO, YASUO |
分类号 |
C12N5/06;A61K38/00;A61P25/00;A61P25/28;A61P43/00;C07H21/04;C07K1/22;C07K7/08;C07K14/47;C07K14/475;C07K14/52;C07K14/54;C07K14/545;C07K14/55;C07K14/705;C07K14/71;C07K14/715;(IPC1-7):A61K38/18;C07K11/00 |
主分类号 |
C12N5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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