| 摘要 |
<p>New 15,15-dialkyl-substituted derivatives of the estradiol of general formula (I), in which R?1 and R2¿, independently of one another, are each a hydrogen atom or a straight-chain alkanoyl group with 1 to 10 carbon atoms, a branched-chain alkanoyl group with 3-10 carbon atoms, an alkanoyl group of 3-10 carbon atoms containing a cycloaliphatic structure of 3-6 carbon ring atoms or a benzoyl group, and R?3 and R4¿, independently of one another, are each a straight-chain alkyl group with 1 to 10 carbon atoms, or a branched-chain alkyl group with 3 to 10 carbon atoms, are described, a process for their production and initial products for this process. The new compounds have -- also after oral administration -- high estrogenic effectiveness and are suitable for the production of pharmaceutical agents.</p> |
