| 摘要 |
This invention relates to pharmaceutical compositions for use in the prevention, treatment and relief of indigestion, sour stomach, heartburn, gastroesophageal reflux, dyspepsia, constipation, over-indulgence and other gastrointestinal disorders in mammals, including humans, by administering compositions comprising: (i) an amount effective in the relief of gastrointestinal or esophagus disorders of an H2 antagonist selected from a compound of formula (I) and pharmaceutically acceptable salts, hydrates, stereoisomers or polymorphs thereof, and (ii) an amount effective in the relief of gastrointestinal or esophagus disorders and in the promotion of gastric emptying of a gastrointestinal motility agent such as cisapride, and optionally (iii) an amount effective in the relief of flatulence of simethicone or alpha-D-galactosidase. |
