发明名称 |
Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents |
摘要 |
2139738 9426313 PCTABS00034 Complexes of bicyclopolyazamacrocyclocarboxylic acid with Gd, Mn or Fe ions are disclosed. The complexes can be covalently attached to a biologically active molecule, e.g. an antibody or antibody fragment, to form conjugates. The complexes and conjugates are useful as contrast agents for diagnostic purposes. Processes for preparing both the complex and conjugate are disclosed. |
申请公布号 |
AU4237993(A) |
申请公布日期 |
1995.02.02 |
申请号 |
AU19930042379 |
申请日期 |
1993.05.06 |
申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
GARRY E. KIEFER;JAIME SIMON |
分类号 |
C07D471/06;A61K49/00;A61K49/06;A61K49/08 |
主分类号 |
C07D471/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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