发明名称 PHARMACEUTICAL COMPOSITIONS CONTAINING AS ACTIVE AGENT ISOFLAVONE DERIVATIVES OR SALTS THEREOF
摘要 The present invention relates to pharmaceutical compositions containing as active agent isoflavone derivatives of general formula (I), wherein R1 represents a C2-C18alkyl optionally substituted by C1-6alkoxy, hydroxyl, C1-6carbalkoxy, phenyl, benzoyl or a halo atom; phenylalkyl containing a C1-3alkyl chain optionally substituted by a halo atom or a nitro group or C2-6alkenyl; R2 and R3 stand for hydrogen or C1-6alkoxy; R4 stands for hydrogen, C1-6alkyl or carboxyl; R5 stands for hydrogen or C1-4alkyl; R6 stands for hydrogen or, if R5 stands for hydrogen, R6 may also stand for methyl or hydroxymethyl, with the proviso that if R2, R3, R4, R5 and R6 stand for hydrogen, R1 is other than isopropyl, or salt thereof. The pharmaceutical compositions according to the invention are prepared by known methods and are suitable for the treatment of osteoporosis.
申请公布号 CA2167597(A1) 申请公布日期 1995.02.02
申请号 CA19942167597 申请日期 1994.07.18
申请人 CHINOIN LTD. (SHORT FORM OF: CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS CO.) 发明人 NOGRADI, MIHALY;GOTTSEGEN, AGNES;ANTUS, SANDOR;STRELISKY, JANOS;VERMES, BORBALA;WOLFNER, ANDRAS;MAJOR, ADAM;SZUETS, TAMAS;BENDEFFY, ISTVANNE;MARMAROSI, TAMASNE
分类号 C07D311/36;C07D311/38;(IPC1-7):A61K31/35 主分类号 C07D311/36
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