发明名称 Lipohaptens and use of carrier-bound lipohaptens in immunoassays.
摘要 Lipohaptens of the general formula I (X)m-R-Y-(S)n-P (I) wherein - R is a hydrocarbyl backbone having from 2 to 30 carbon atoms - X is a hydrocarbyl radical having from 6 to 30 carbon atoms, which is linked to R via a bonding group containing one or more heteroatoms - m is an integer from 1 to 5 - P is a polypeptide or polysaccharide residue having from 2 to 100 aminoacid or glycosyl units - Y is a functional group capable of binding to a free amino group of the polypeptide P or a carboxy, hemiacetal or hydroxy group of the polysaccharide P - S is a difunctional spacer group, the functional groups thereof being capable of binding with the functional group Y on the one hand and a free amino, carboxy or hydroxy group of the polypeptide or polysaccaride P on the other hand, and - n is 0 or 1 and their use in immunoreactions for determining antibodies and antigens, respectively.
申请公布号 EP0374296(B1) 申请公布日期 1995.02.01
申请号 EP19880121536 申请日期 1988.12.22
申请人 BAXTER DIAGNOSTICS INC. 发明人 STOFFEL, WILHELM DR
分类号 G01N33/531;G01N33/543;G01N33/92 主分类号 G01N33/531
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