Method for producing L-3,4-dihydroxyphenylalanine.

摘要

In a method for producing L-3,4-dihydroxyphenylalanine by subjecting microorganism cells having a beta -tyrosinase activity or a product to be obtained by processing them to catalytic reaction with catechol, pyruvic acid and ammonium ion or with catechol and L-serine, the reaction is continued at a temperature lower than 25 DEG C under the condition where anhydrous crystals of L-3,4-dihydroxyphenylalanine exist in the reaction mixture while L-3,4-dihydroxyphenylalanine being formed are made precipitated as anhydrous crystals in the reaction mixture, and the thus-precipitated anhydrous crystals are collected. According to the method of the present invention, crude crystals of L-3,4-dihydroxyphenylalanine having a high purity may be obtained at a high yield of recovery, by simple means.