AMINOBENZOIC ACID DERIVATIVES

摘要

To provide a compound which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio. An aminobenzoic acid derivative represented by the general formula (I) or (II) or a pharmacologically acceptable salt thereof: <IMG> (I) <IMG> (II) ¢wherein R1 represents a group represented by the formula: <IMG> , <IMG> , <IMG> etc., {wherein A represents a group represented by formula -CH2-X-CH2- (wherein X represents O, >N-R6 or >CHR7 (wherein R6 represents lower alkyl and R7 represents hydrogen or lower alkoxy)), etc.; D and E each represents a group represented by formula -(CH2)3-, etc., and R2 represents lower alkyl, etc.}; R9 represents alkynyl; R10 represents amino, etc.; R11 represents halogen; R12 and R13 each represent lower alkyl; a is an integer of 1 to 5; and b is an integer of 0 to 5!.