发明名称 PIPERIDINE AND PIPERAZINE
摘要 Piperidine and piperazine derivatives of the formula I <IMAGE> in which R<1> and R<2> are H or A, R<3>, R<4> and R<5> in each case independently of one another are H, Hal, OH, OA, OAc, NO2, NH2, NHAc, NHSO2A or CN, or R<3> and R<4> together are also -O-(CH2)m-O-, n is 0, 1 or 2, X is O or CH2 if n = 0 or 2, or CH2, NH, NA or NAc if n = 1, Y is CH or N, m is 1 or 2, Hal is F, Cl, Br or I, A is alkyl having 1-6 C atoms and Ac is alkanoyl having 1-8 C atoms, aralkanoyl having 1-10 C atoms or aroyl having 7-11 C atoms, and their physiologically acceptable salts have antiarrhythmic effects.
申请公布号 JPH0725851(A) 申请公布日期 1995.01.27
申请号 JP19940136940 申请日期 1994.06.20
申请人 MERCK PATENT GMBH 发明人 MANFUREETO BAUMUGARUTO;INGE RIYUSU;KURAUSUUOTSUTOO MINKU;NORUBERUTO BAIAA
分类号 A61K31/445;A61K31/4427;A61K31/443;A61K31/451;A61K31/47;A61K31/495;A61P9/06;C07D211/14;C07D211/18;C07D211/22;C07D211/26;C07D211/28;C07D211/34;C07D215/12;C07D295/04;C07D295/08;C07D295/096;C07D307/81;C07D313/08;C07D319/18;C07D401/06;C07D405/06;C07D405/14 主分类号 A61K31/445
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