PROCESS FOR THE PREPARATION OF N-CARBONYLARYLIMINES USEFUL FOR THE SYNTHESIS OF THERAPEUTICALLY ACTIVE TAXOIDS

摘要

Process for the preparation of N-carbonylarylimines of general formula (I) by desulphonating a sulphone of general formula (II). The N-carbonylarylimines of general formula (I) are particularly useful for the preparation of therapeutically active taxoids from baccatin III or 10-deacetyl baccatin III. In general formulae (I) and (II), Ar is an aryl radical, R is a t.butoxy or phenyl radical and Ph is an optionally substituted phenyl radical.