摘要 |
<p>An object of the present invention is to provide piperazine derivative and salt thereof having inhibitory effect against superoxide radicals (O2-). The piperazine derivative of the present invention is represented by formula (1) (wherein R1 is a lower alkyl group; R2 is a phenyl-lower alkyl group which may have 1 to 3 substituents, on the phenyl ring, selected from the group consisting of a hydroxyl group, a phenyl-lower alkoxy group, a lower alkyl group, a lower alkoxy group and a halogen atom; R3 is a hydrogen atom, a lower alkyl group or a phenyl-lower alkyl group; and R4 is a hydroxyl group, a phenyl-lower alkoxy group or a tetrahydropyranyloxy group).</p> |