发明名称 IDENTIFICATION OF LIGANDS BY SELECTIVE AMPLIFICATION OF CELLS TRANSFECTED WITH RECEPTORS
摘要 A method of detecting a substance capable of acting as a ligand, the method comprising: (a) incubating, under conditions permitting cell amplification, cells transfected with DNA coding for a receptor capable of influencing cell amplification in response to a ligand, the cells comprising a marker of cell amplification, with a test substance which is a potential agonist or antagonist of the receptor, and (b) after a period of time sufficient to permit cell amplification, determining the presence or absence of amplification of cells containing the marker relative to cells not containing the marker.
申请公布号 WO9502823(A1) 申请公布日期 1995.01.26
申请号 WO1994US07900 申请日期 1994.07.13
申请人 BRANN, MARK, ROBERT 发明人 BRANN, MARK, ROBERT
分类号 C07K14/705;C12N5/10;C12N15/09;C12P21/02;C12Q1/68;G01N33/50;G01N33/566;G01N33/58;G01N33/74;(IPC1-7):G01N33/566 主分类号 C07K14/705
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