发明名称 |
RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS |
摘要 |
Chelating compounds of specified structure are useful for radiolabeling targeting proteins such as antibodies as well as proteinaceous and non-proteinaceous ligands and anti-ligands. The radiolabeled antibodies, ligands or anti-ligands, or catabolites thereof, demonstrate improved biodistribution properties, including reduced localization within the intestines.
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申请公布号 |
CA2165052(A1) |
申请公布日期 |
1995.01.26 |
申请号 |
CA19942165052 |
申请日期 |
1994.07.12 |
申请人 |
NEORX CORPORATION |
发明人 |
GUSTAVSON, LINDA M.;KASINA, SUDHAKAR;FRITZBERG, ALAN R. |
分类号 |
A61K51/04;A61K51/10;C07F13/00;C07K5/06;C07K5/078;(IPC1-7):C07K5/06;C07B59/00;C07F15/00;C07H23/00;C07K9/00;C07D495/04;C07H5/06;C07F1/08 |
主分类号 |
A61K51/04 |
代理机构 |
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