发明名称 Diurea derivatives useful as medicaments and processes for the preparation thereof
摘要 Diurea derivatives are provided which can be represented by the following general formula and salts thereof: <IMAGE> wherein, R1 and R2 are the same or different, and each represents C1-10 alkyl group, a C3-18 cycloalkyl group, or a lower alkyl group substituted by cycloalkyl radical(s); R3, R4, R5 and R6 are the same or different, and each represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, hydrocarbyl aralkyl group, a pyridyl group, or an unsubstituted or substituted phenyl group, the substituents of the phenyl group being selected from a group consisting of lower alkyl radical, halogen atom-substituted lower alkyl radical, halogen atom, nitro radical, amino radical, mono- or di-lower alkylamino radical, lower acylamino radical, hydroxyl radical, lower alkoxy radical and lower acyloxy radical; X represents an oxygen atom or a sulfur atom, and n1 and n2 represent an integer of 1 to 6; and wherein at least one of R3-R6 is a phenyl substituted by acyloxy.
申请公布号 US5384425(A) 申请公布日期 1995.01.24
申请号 US19930064850 申请日期 1993.10.07
申请人 YAMANOUCHI PHARMACEUTICAL CO., LTD. 发明人 ITO, NORIKI;YASUNAGA, TOMOYUKI;IIZUMI, YUICHI;ARAKI, TOMIO
分类号 C07C275/26;C07C275/28;C07C275/30;C07C275/34;C07C275/40;C07C335/14;C07D213/75;(IPC1-7):C07C69/017 主分类号 C07C275/26
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