发明名称 |
Screen for inhibitors or melanin biosynthesis. |
摘要 |
<p>A method for the identification of agents that inhibit melanin biosynthesis involves the incubation of test samples in cultures of a fungus that produces melanin. Observation of altered pigmentation in the culture or culture area containing test sample indicates inhibition of melanin biosynthesis. Preferred cultures for the screen contain a fungus that pigments in the light or the dark such as Cladosporium cucumerinum. Preferred embodiments employ test samples on disks or in wells in solidified cultures and a known melanin synthesis inhibitor as a positive control which is compared to the test sample by simple visual inspection.</p> |
申请公布号 |
EP0635577(A2) |
申请公布日期 |
1995.01.25 |
申请号 |
EP19940109776 |
申请日期 |
1994.06.24 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
BRINDLE, FRANCES HARRIET ELIZABETH;FROELIGER, EUNICE HARRIET |
分类号 |
C12Q1/02;(IPC1-7):C12Q1/04 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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