发明名称 |
INHIBITION OF PHOSPHATIDYLINOSITOL 3-KINASE WITH WORTMANNIN AND ANALOGS THEREOF |
摘要 |
of the Invention Wortmannin and certain of its analogs are inhibitors of phosphatidylinositol 3-kinase. The compounds are particularly useful for inhibiting phosphatidylinositol 3-kinase in mammals and for treating phosphatidylinositol 3-kinase-dependent conditions, especially neoplasms, in mammals.
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申请公布号 |
CA2128046(A1) |
申请公布日期 |
1995.01.20 |
申请号 |
CA19942128046 |
申请日期 |
1994.07.14 |
申请人 |
ELI LILLY AND COMPANY;ARIZONA BOARD OF REGENTS (THE) |
发明人 |
BONJOUKLIAN, ROSANNE;POWIS, GARTH;VLAHOS, CHRIS J. |
分类号 |
A61K31/58;A61K31/34;A61K31/343;A61K31/365;A61K31/585;A61P35/00;A61P43/00;C07D307/77;(IPC1-7):A61K31/365 |
主分类号 |
A61K31/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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