发明名称 |
Methods of diagnosing pre-cancer or cancer states using probes for detecting mutant p53 |
摘要 |
A panel of probes that detect and distinguish between sets of human p53 gene or protein mutations that frequently occur or are selected for in pre-cancer and cancer cells, each set giving rise to a phenotype that is different from that of wild-type p53 and of at least one other set of p53 mutants.
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申请公布号 |
US5382510(A) |
申请公布日期 |
1995.01.17 |
申请号 |
US19920912011 |
申请日期 |
1992.07.10 |
申请人 |
THE TRUSTEES OF PRINCETON UNIVERSITY |
发明人 |
LEVINE, ARNOLD J.;SHENK, THOMAS E.;FINLAY, CATHY A. |
分类号 |
C07K14/435;C07K14/00;C07K14/47;C07K14/475;C07K16/00;C07K16/22;C07K16/32;C12N5/10;C12N15/09;C12P21/08;C12Q1/68;G01N33/53;G01N33/574;G01N33/577;G01N37/00;(IPC1-7):C12Q1/68 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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