摘要 |
A selective serotonin reuptake inhibitor such as sertraline is used in combination with lithium for simultaneous or separate, including concurrent, administration in a method of achieving rapid onset of antidepressant action in a patient. Onset of antidepressant action is observed with such preparations approximately one week earlier than that achievable through the administration of the selective serotonin reuptake inhibitor alone. Such rapid onset of action is extremely significant in the case of patients who are severely depressed. |