A tube knot applicator for use in endosurgical procedures. The tube knot applicator has an elongated tube member having a distal end and a proximal end, as well as an axial passage therethrough. The tube member has slits for partially collapsing the distal end of the tube as well as a removable plug mounted in the distal end of the tube to prevent the distal end of the tube from collapsing by supporting distal slitted end. A suture having at least one slip knot and at least one locking knot is mounted in the tube knot applicator with the knot tied about the collapsing means. A sleeve is mounted to the distal end of tube knot applicator over the suture knot and the distal end.